Penn Dental Medicine

Departments & Faculty

George Hajishengallis, DDS, PhD

Thomas W. Evans Centennial Professor
Department of Microbiology


  • D.D.S., University of Athens, Greece, 1989
  • Ph.D., University of Alabama at Birmingham, 1994


  • Assistant Professor, Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, 2003-2005.
  • Research Excellence Awards, Louisiana State University School of Dentistry, 2004 & 2005
  • Reviewer for NIH Scientific Review Group ODCS & Special Emphasis Panels (since 2005)
  • Associate Professor, School of Dentistry (Department of Periodontics) and School of Medicine (Department of Microbiology and Immunology), University of Louisville, 2005-2008
  • Japanese Society for the Promotion of Science (JSPS) fellow, 2008
  • Professor, School of Dentistry (Department of Oral Health and Rehabilitation) and School of Medicine (Department of Microbiology and Immunology), University of Louisville, 2008-2011
  • University Scholar, University of Louisville, 2005-2010
  • Distinguished University Scholar, University of Louisville, 2010-2011
  • Institutional Animal Care and Use Committee (IACUC) member, University of Louisville, 2008-2010
  • Associate Director, Center for Oral Health and Systemic Disease, University of Louisville, 2010-2011
  • External Scientific Advisory Board, European Commission Community Research and Development Information Service (CORDIS), 2010-present
  • Associate Editor, Journal of Immunology (2009-present) and Molecular Oral Microbiology (2009-present)
  • Review Editor, Frontiers in Molecular Innate Immunity, 2011-present
  • Featured in the AADR’s Strides in Science, 2011
  • 2012 IADR Distinguished Scientist Award in Oral Biology
  • 2014 AADR/IADR William J. Gies Award in the Biological Research Category
  • NIH MERIT Award, 2016

Research Interests

Dr. Hajishengallis is a Professor of Microbiology at Penn Dental Medicine. His field of interest lies at the interface of microbial pathogenesis and immunity, and his work has illuminated important mechanisms of immunopathogenesis of well-adapted pathogens that exploit the human immune system and subvert it to their own advantage. His interests also include the impact of aging on inflammatory diseases. He further combines basic scientific and translational research, leading to novel approaches to clinical problems, such as are exemplified by periodontal disease. His discoveries have led to several invention disclosures and patent applications. Dr. Hajishengallis’s studies have been published in several prestigious journals of general scientific interest including Nature Immunology, Cell Host & Microbe, PNAS, and Science Signaling, as well as leading disciplinary journals such as the Journal of Immunology, and Journal of Dental Research.

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George Hajishengallis, DDS, PhD
The Robert Schattner Center
University of Pennsylvania
School of Dental Medicine
240 South 40th Street
Philadelphia, PA 19104-6030