Center for Clinical and Translational Research

Providing centralized support to researchers within Penn Dental Medicine who conduct human subjects research. Our highly specialized Center provides clinical research support and services spanning the full spectrum of a study from conceptualization to closeout for industry, federal, and foundation sponsors.


Spotlighted Study

The Rembrandt StudyThe Rembrandt Study: Recovery of the Microbiome from Antibiotics for Dental Implants
Principal Investigators: Laurel Redding, VMD, PhD, DACVPM and Yu Wang, DMD, MS
Study Status: Currently enrolling
This Study is Grant Funded by: the Human-Animal Bond Research Institute and the National Institutes of Health

This collaborative study between Penn Dental and Penn Vet is an observational study of patients who will be receiving dental implants. The purpose of the study is to determine whether owning a pet changes the disruption and recovery of a person’s microbiome (collection of bacteria in the intestines) after they have received antibiotics for a dental implant. Eligible participants will be asked to collect stool samples from themselves (and from their pets if they are pet owners) once before their implant procedure and at 4 different sampling dates following their procedure (3, 10, 30 and 90 days after). All samples can be collected at home, and participants will be provided with study materials for sample storage and shipment.

You may be eligible to participate if you are aged 50 years or older and are scheduled to receive a dental implant. If you are interested in learning more about the study, please contact the study team at 484-999-1545,



For more information »

For information on how to support the work of the Center for Clinical and Translational Research, please contact:

Elizabeth Ketterlinus
Vice Dean of Institutional Advancement