Providing centralized support to researchers within Penn Dental Medicine who conduct human subjects research. Our highly specialized Center provides clinical research support and services spanning the full spectrum of a study from conceptualization to closeout for industry, federal, and foundation sponsors.

Penn Dental Medicine’s Center for Clinical and Translational Research (CCTR) is proud to be recognized through the American Dental Association’s Qualified Testing Sites Program. This designation reflects CCTR’s ability to support high-quality clinical research and product testing in an academic setting with rigorous oversight, experienced study teams, and access to a diverse patient population.
As an ADA Qualified Testing Site, CCTR offers industry partners and investigators a trusted environment for the evaluation of oral health products and technologies. Through this partnership, CCTR is well positioned to support manufacturers seeking independent clinical testing and reliable study execution across qualified categories.
To learn more about partnering with CCTR on clinical research and product evaluation, please contact our team.
Mechanisms of variability in the analgesic response to ibuprofen following third molar extraction
Principal Investigator: Dr. Katherine N. Theken, PharmD, PhD
Study Status: Currently Enrolling
The purpose of this study is to learn how patients who have their wisdom teeth removed respond to the pain-relieving drug ibuprofen. The wisdom tooth extraction surgery will be performed as standard of care. After surgery, patients will be administered ibuprofen and acetaminophen. Patients that may experience severe pain will be given oxycodone to relive the pain.
During the study visits, blood, urine and stool samples will be collected. Additionally, we will collect oral swabs. You may also be asked to complete some questionnaires. The study consists of 4 study visits. In which compensation will be provided per visit (visit-1 $50, visit-2 $100, visit-3 $100, visit-4 $100).
Learn more about the VARI Study here »
Interested in connecting with CCTR? Follow us on Linkedin.
For information on how to support the work of the Center for Clinical and Translational Research, please contact:
Maren Gaughan
Associate Dean of Leadership Giving
gaughan@upenn.edu
Dr. Eugene Ko
Deputy Director, Clinical Research Operations
eugko@upenn.edu
Rosa Urbina
Associate Director of Research Coordination and Regulatory Services
rurbina@upenn.edu