CDE: [The Dean's Speaker Series] I SEE YOUR PAIN! Navigating Through the Patient’s Brain in the Clinical Environment – Objectively Measuring Pain Using Neuroimaging, Augmented Reality and Artificial Intelligence

Oct, 2019
12:00 PM-01:00 PM

Penn Dental Medicine
William W.M. Cheung Auditorium

Time: 12:00 – 1:00 pm | Lunch provided
Registration Fee: Free; Registration is required for CE credit.
CE Credits: 1.0 lecture credits


Pain is the most common reason for seeking medical care, and for many patients, pain severely impairs their daily life. Chronic pain alone affects 116 million Americans costing an estimated $635 billion each year. Dr. Alex DaSilva will provide evidence of how the human brain is affected by pain, and how this pain and its treatment modulate the endogenous opioid system. Also, he will discuss the new frontiers in pain research, education, and treatment that include: real-time brain activity visualization using neuroimaging in the clinical environment, augmented reality, artificial intelligence, neuromodulation, mobile applications, and learning health systems.

Educational Objectives

  • Have an updated understanding ofbrain mechanisms underlying acute and chronic pain (MRI-based and PET [e.g., mu-opioid receptor]);
  • Be able to critically discuss novel neuroimaging technologies that can be used in the clinical environment to monitor brain activity before, during and after dental pain;
  • Discuss a step-by-step process of clinical neuro-augmented reality protocol to measure pain objectively using optical neuroimaging, augmented reality and artificial intelligence.


Alexandre DaSilva, DDS, DMedSc, is an Associate Professor in the Department of Biologic & Materials Sciences, University of Michigan School of Dentistry. Dr. DaSilva received his Doctorate in Medical Science degree in Oral Biology with clinical training in Orofacial Pain at Harvard University. He is the Founder and Director of H.O.P.E. (Headache & Orofacial Pain Effort) laboratory, a multidisciplinary collaborative effort to investigate the brain as a research and therapeutic target for pain. The H.O.P.E. Lab focuses on the development of clinical and neuroscience-driven tech-innovations for human neuroimaging (PET, MRI, fNIRS, EEG), neuromodulation, mobile technology, artificial intelligence, augmented/virtual reality, and their integration for pain research, education, and treatment. Dr. DaSilva has been a frequent speaker for multiple national and international scientific meetings. His funded research projects focus on the evaluation and modulation of opioid mechanisms in the brains of chronic pain patients in vivo. His publications have received broad media coverage by national and international venues, for instance, Discovery Channel, San Francisco Chronicle, Scientific American Mind, and others.

Disclosure: Dr. Alexandre F. DaSilva co-created GeoPain and CLARAi and also co-founded MoxyTech Inc, a spinoff startup that licensed the technologies from the University of Michigan.

University of Pennsylvania School of Dental Medicine is an ADA CERP Recognized Provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry.

University of Pennsylvania School of Dental Medicine designates this activity for 1.0 continuing education credits.