Home // News & Events // CDE: [The Dean’s Speaker Series] Inter-individual variability in cardiovascular risk and analgesic response to NSAIDs

CDE: [The Dean’s Speaker Series] Inter-individual variability in cardiovascular risk and analgesic response to NSAIDs

29
Oct, 2019
12:00 PM-01:00 PM

Penn Dental Medicine
William W.M. Cheung Auditorium

Time: 12:00 – 1:00 pm | Lunch provided
Registration Fee: Free; Registration is required for CE credit.
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CE Credits: 1.0 lecture credits

Description

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used medications worldwide. They are an important non-addictive option for pain relief, and optimizing NSAID therapy is one strategy to address the current opioid crisis. However, NSAIDs also have the potential to cause serious adverse cardiovascular events, most notably myocardial infarction, stroke, and heart failure. This talk will discuss ongoing work investigating factors that contribute to inter-individual variability in cardiovascular risk and analgesic efficacy of NSAIDs.

Educational Objectives

  • Describe the mechanism of action of NSAIDs and how this relates to cardiovascular risk and analgesic efficacy.
  • Compare and contrast naproxen and celecoxib with regard to pharmacological potency and effect on blood pressure.
  • Describe factors that contribute to inter-individual variability in analgesic response to NSAIDs following third molar extraction.

Speaker

Katherine N. Theken, PharmD, PhD, completed her PharmD at the University of Pittsburgh and PhD in Pharmaceutical Sciences at the University of North Carolina Eshelman School of Pharmacy. She completed he post-doctoral training with Garret FitzGerald (UPenn, Department of Systems Pharmacology and Translational Therapeutics/ITMAT). Her research investigates the factors that contribute to inter-individual variability in drug response and adverse events.

Disclosure: Dr. Theken has no relevant financial relationships to disclose.


University of Pennsylvania School of Dental Medicine is an ADA CERP Recognized Provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry.

University of Pennsylvania School of Dental Medicine designates this activity for 1.0 continuing education credits.