Frank C Setzer received the his dental and doctoral degree from the Friedrich-Alexander-University Erlangen-Nuremberg, Germany in 1995 and 1998; and his Endodontic specialty certificate, MS in Oral Biology and DMD from the University of Pennsylvania, Philadelphia, PA, USA in 2006, 2008, and 2010, respectively. He is currently an Associate Professor of Endodontics at the University of Pennsylvania, serving as Predoctoral Director in Endodontics. His research interests are the clinical detection, prognosis and assessment of periradicular pathology, in particular apical periodontitis, utilizing CBCT imaging and Artificial Intelligence, as well as endodontic microsurgery. Dr. Setzer is a dental faculty member of OKU, a member of the American Association of Endodontists AAE, and a Diplomate of the American Board of Endodontics ABE. In addition, he is Associate Editor for Journal of Endodontics and the European Endodontic Journal, serves on several others editorial review boards, and lectures at national and international conferences.