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Kyle Vining

Kyle Vining, D.D.S., Ph.D.

Assistant Professor of Preventive and Restorative Sciences, School of Dental Medicine and Department of Materials Science, School of Engineering & Applied Sciences

Division of Restorative Dentistry, Preventive & Restorative Sciences

Levy Building, Room 248

Email: viningk@upenn.edu

Professional Biography

Dr. Vining’s research investigates mechanical regulation of tissue inflammation in bone marrow disease and head and neck cancer. He is also developing strategies to target inflammation and promote tissue repair and regeneration in oral and craniofacial diseases. Among his projects in the area of biomaterials development, he developed a fibrotic extracellular matrix hydrogel to investigate the effects of mechanical cues in fibrotic niches. He also engineered a novel antimicrobial coating for titanium dental implants and developed a new polymeric dental material that supports differentiation and proliferation of dental pulp stem cells for regenerative dentistry applications. His most recent work was published in Nature Materialshttps://www.nature.com/articles/s41563-022-01293-3.

Vining Lab »

Highlighted Honors/Credentials
  • Patent issued – Adam D. Celiz, Kyle Holmberg Vining, David J. Mooney. (2022) Methods and compositions for dental tissue repair and/or regeneration. US Patent. 11,224,679.
  • NIH K99 Award (K99DE030084) – Targeting Mechanical Regulation of Monocyte Fate in Head and Neck Cancer, NIDCR, 2021-22
  • Councilor, Oral and Maxillofacial Surgery Research Group, International Association of Dental Research (IADR), 2021-23
  • Abstract Achievement Award, American Society of Hematology, 2021
  • Science First Task Force, American Association of Dental, Oral, and Craniofacial Research (AADOCR), 2021
  • First Place, AADOCR Hatton Competition, Senior Category, 2021
  • NIH K08 Award (K08DE025292) – Anti-Inflammatory Mesenchymal Stem Cell Therapy for Dental Applications, NIDCR, 2016-2021
  • Second Place, Emerging Technologies Competition, Royal Society of Chemistry, London, UK, 2016
  • Teaching Fellow, Introduction to Biomaterials, School of Engineering and Applied Sciences, Harvard University, 2016
  • Henry M. Thornton/SCADA Fellowship Award, 2014-2015
  • Scholarship for Dental Students Pursuing Academic Careers, American Dental Education Association (ADEA), 2014
  • First Place, IADR and AADR Hatton Competitions, Junior Category, Seattle, Washington, 2013
  • Wrigley Clinical Salivary Research Award for Dental Students, 2013
  • Rapid Fire Poster Award, World Biomaterials Congress, Chengdu, China, 2012
  • Biomedical Engineering Honors and Best Research Award, Northwestern University, 2009

Curriculum Vitae »

Education
  • Postdoctoral Scientist, Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 2021-2022
  • Ph.D. in Engineering Sciences (Bioengineering), Harvard University, Cambridge, MA, 2014-2020
  • D.D.S., University of Minnesota School of Dentistry, Minneapolis, MN, 2009-2014
  • Fellow, NIH Medical Research Scholars Program, NIDCR/NIH, Bethesda, MD, 2012-2013
  • B.S. in Biomedical Engineering, Northwestern University, Evanston, IL, 2005-2009
Laboratory Site

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Selected Publications

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