Program-Specific Curriculum

This course in Oral Medicine meets weekly and will allow academic discussion of disease and disease processes, as well as therapeutic management of a wide range of topics related to the field of Oral Medicine including but not limited to, oral-mucosal disease, orofacial pain, salivary gland diseases, infectious disease, oral pathology, oral radiology, and internal medicine. In addition, this course allows students to present and discuss recent scientific articles related to the field of oral medicine. Students will develop the ability to critically review papers. Residents will meet with faculty members to discuss recent literature in their field of interest and/or expertise.

This conference meets weekly and provides residents with didactic training in the fundamentals of oral medicine, including oral mucosal diseases, orofacial pain syndromes, oral pathology, oral and maxillofacial radiology, laboratory medicine, internal medicine, pharmacology, and research methodology. The lectures are given by faculty within the Department of Oral Medicine and the University of Pennsylvania School of Dental Medicine.

This course introduces residents to the techniques and principles needed for the histopathologic evaluation of biopsy specimens. These include grossing, orienting and mounting specimens, various staining techniques, and the principles of microscopic diagnosis.

Residents will spend time with departmental faculty diagnosing and treating patients with a variety of disorders related to oral medicine.

Residents will spend time in the medically complex patient clinic providing general dental care to patients with a multitude of complicating medical diagnoses in an outpatient setting.

This course, offered through the Department of Oral and Maxillofacial Surgery at the Hospital of the University of Pennsylvania, is designed to cover topics relevant for residents involved in the on-call service, including maxillofacial infections, trauma, and advanced head and neck anatomy.

After developing of a research proposal, residents will perform clinical or laboratory research. A variety of topics and projects are available through The Leon Levy Center for Oral Health Research. Following the successful defense of a thesis, a Master in Oral Biology will be conferred. For both the two- and three-year tracks, it is expected that each resident will be involved in the preparation of at least one paper eligible for publication in a peer-reviewed journal. Presentation of abstracts and posters at annual scientific meetings is encouraged.

Core Graduate Dental Education Curriculum

Objectives: The purpose of this lecture series is to review the principal anatomy comprising the stomatognathic system. The lectures build on the knowledge of head and neck anatomy acquired in dental school and integrates clinical relevance to this important subject. Slide presentations are employed to teach the anatomical structures of the major head and neck morphologic systems. The course focuses on the clinically pertinent aspects of the basic anatomy. Aspects of anatomy that are vital to patient care are emphasized. The course reviews common disorders pertaining to head and neck anatomy, their diagnosis and management. Thus, a broad perspective of the major anatomical points and their functional importance is obtained. A final essay examination is employed to assess competence and knowledge of materials presented.

Objectives: 1. To gain an in-depth knowledge of therapeutic agents commonly employed in dental practice, including local anesthetic, sedative-hypnotic analgesia, and antibiotic drugs. 2. To explore evidence-based research as it relates to drug interaction in dental practice. 3. To learn how to prescribe and administer drugs to medically complex patients.

Objectives: 1. To give the student an understanding of the normal and abnormal biology of the dentin-pulp complex. 2. To provide the student with fundamental information on clinically related subjects such as pain control and pulp capping procedures. 3. To provide the student with a general knowledge of the literature related to pulp biology. 4. To review the various physiological methods of investigating pulpal tissue.

Objectives: To provide a sufficiently in-depth introduction to statistics and the concepts of probability so that students can: 1. review and critically evaluate the use of statistics in the research literature. 2. set up and carry out statistical tests on their own data. 3. communicate effectively with statisticians and biometricians.

Objectives: The educational objective of the Microbiology component of the core curriculum is to provide the students an updated overview of several current broad areas of oral microbiology important to practicing dentists. After taking this course the students should understand: 1. the general differences between oral bacteria, viruses and their own cells 2. how microbiology testing services separate and identify certain microbial species in dental plaque and crevicular fluid samples 3. how the commonly used antibiotics control microbial infections 4. how bacteria develop resistances to the commonly used antibiotics 5. the role of oral bacteria in the development of human dental plaque 6. the current theories of caries formation 7. the role of oral bacteria in periodontal diseases 8. the role of human immune response in periodontal diseases 9. the biology of HIV 10. the major clinical manifestations of AIDS

Objectives: To make the students aware of the most current information about congenital craniofacial anomalies, and to be able to develop their specialty dental treatment plans with consideration for these anomalies.

Objectives: 1. To introduce students to recent scientific developments concerning the molecular and genetic regulation of osteogenesis and bone development. 2. To show how recent advances at the fundamental level can be used to further our understanding of clinical disease. 3. To use web-based information to explore the bone literature-base. 4. To review and extend students’ understanding of basic concepts in molecular biology.

Objectives: To have fundamental knowledge and competency in the following: 1.Obtain an adequate history from the patient with oral mucosal disease. 2. Formulate a differential diagnosis regarding oral mucosal disease. 3. Understand at a basic level the pathophysiology regarding each specific disorder named in the course outline. 4. Understand common treatment regimens regarding each specific disorder.

Objectives: To provide students with a basic understanding of the biologic principles involved in osteoimmunology. These include an understanding of the immune response, the osteoclast and osteoblast, the effect of immune cells on osteoblasts and osteoclasts, osteoblast signaling pathways, interactions among bone cells, and the effect of the immune system on clinically important aspects of bone biology including osteoporosis, arthritis, fracture healing, periodontitis, lesions of endodontic origin and orthodontic tooth movement.

Objectives: At the end of the lecture series, the graduate students should be able to: 1. Understand the basic radiographic anatomy of the maxilla, mandible, teeth and supporting tissues using plain intraoral films, computerized tomography and magnetic resonance imaging. 2. Differentiate between paralleling and bisecting angle techniques as used in intraoral radiography and be able to use either of the techniques in various clinical situations. 3. Understand the concepts of standardization in terms of film position and tube position to be able to use similar techniques for clinical research. 4. Understand the concepts in advanced radiophysics, in particular the modern designs in the construction of x-ray tubes and utilization of alternating current and direct current in the production of x-rays 5. Understand the principles of radiobiology and protection, including the safety of the operator and patient, maximum permissible doses, and shielding calculations for operatories. 6. Use the principles of radiographic interpretation for identification and differentiation of all bony lesions, changes in the densities of bone, and bone regeneration. 7. Know the different types of radiographic assessment for implant placement, and understand the causes of implant failure as related to the bone quality. 8. Understand the panoramic anatomy and different types of tomography. 9. Know the concepts of digital radiology including the charged couple devices and the active pixel sensors used commonly in image capture and understand the resolution differences between the plain films and digital images. 10. Be knowledgeable of other extraoral radiographic techniques like sialography, arthrography and radionuclide imaging

Objectives: To acquaint the student with research technology used in several basic science laboratories including: 1. chromatography 2. radio-immune assays 3. electron microscopy To introduce the student to research methodology used in several basic science laboratories including: 1. animal paradigms for pain 2. culturing techniques for viruses 3. genetic sequencing and mapping 4. computer simulation of molecules 5. clinical evaluation of dental agents 6. molecular methods for identification of oral microorganisms

Objectives: 1. Discuss the early cellular events following the tissue surgery. 2. Discuss the role and significance of inflammatory response in wound healing. 3. Discuss the granulation tissue derived from each different cell of tooth supportive tissues. 4. Discuss the concept of regeneration versus repair. 5. Discuss the role of growth factors and cytokines in cell differentiation and expression.

Objectives: This background material presents information in the context of an integrated practice management curriculum. The background material also presents suggested topics for discussion exercises and assignments, in addition to specialty topics given within the residency program curriculum by trained faculty.

Objectives: Pathology is a course that will apply what students have already learned to the study of disease. It is an essential link between the basic and clinical sciences concerned with the mechanisms of disease (e.g., inflammation, neoplasia, and immunopathology) and the disease processes that students will encounter during their careers in dentistry. While the emphasis will be on oral pathology, one must also be familiar with systemic diseases that may impact on the health of the patients.