George Hajishengallis

Thomas W. Evans Centennial Professor

Department of Basic & Translational Sciences

210 Schattner Building

Phone: 215-898-2091


Professional Biography

The field of interest of the Hajishengallis laboratory lies at the host-microbe interface at mucosal surfaces and their work has illuminated novel mechanisms of microbial dysbiosis, inflammation, and tissue homeostasis. More recently, the laboratory has been working also on projects regarding the impact of aging on the immune system, regulation of myelopoiesis and trained innate immunity. The combination of basic scientific and translational research has led to innovative approaches to clinical problems, such as exemplified by complement-targeted inhibition of periodontal disease. The research program of the laboratory is mainly supported by the NIH/NIDCR and has published over 170 papers (with over 14,000 citations), including publications in journals of general scientific interest, such as Cell, Nature Immunology, Science Translational Medicine, Cell Host & Microbe, New England Journal of Medicine, Journal of Clinical Investigation, Nature Communications, PNAS, Science Signaling, Nature Reviews Immunology, and Nature Reviews Microbiology. The laboratory’s research has been featured in Nature Reviews, Faculty of 1000-Biology, the NIH/NIDCR website, Scientific American, AAAS Science Update, WHYY-FM (NPR, Philadelphia) and the popular press. Dr. Hajishengallis was awarded the Distinguished Scientist Award in Oral Biology from the International Association of Dental Research (IADR) in 2012 and a MERIT award from the NIH in 2016. He has listed as a Highly Cited Researcher (Cross-Field category) by Clarivate Analytics in 2018.


2018: Highly Cited Researcher (Cross-Field category; Clarivate Analytics)

  • NIH MERIT Award (2016)
  • Advisory Board Member, Aegean Conferences (2016-present)
  • Thomas W. Evans Centennial Professor, University of Pennsylvania, Penn Dental Medicine (2015-present)
  • AADR/IADR William J. Gies Award in the Biological Research Category (2014)
  • Member of the IADR Distinguished Scientist Awards Committee (2013-2017); Chair of the IADR Subcommittee for the Research in Oral Biology Award (2016-2017)
  • IADR Distinguished Scientist Award in Oral Biology (2012)
  • Research highlighted in Nature Reviews, Faculty of 1000-Biology, NIH/NIDCR website, Scientific American, AAAS Science Update, AADR’s Strides in Science, WHYY-FM (NPR, Philadelphia) and the popular press
  • Editor, Current Topics in Innate Immunity II – Springer (2012); Oral Microbiology and Immunology 2nd ed. – ASM Press (2014)
  • Associate Editor, Journal of Immunology (2009-2013), Molecular Oral Microbiology (2009-present); Journal of Clinical Periodontology (2017-present). Editorial Board Member, Journal of Dental Research (2008-2010 & 2016-present).
  • Distinguished University Scholar, University of Louisville (2010-2011)
  • University Scholar, University of Louisville (2005-2010)
  • Japanese Society for the Promotion of Science (JSPS) fellow (2008)
  • Reviewer for NIH Scientific Review Groups (since 2005); Standing Member, NIH/NIDCR Special -Grants Review Committee (DSR) (2014-present)
  • Faculty Research Excellence Awards, Louisiana State University School of Dentistry (2004 & 2005)”
  • D.D.S., University of Athens, Greece, 1989
  • Ph.D., University of Alabama at Birmingham, 1994
Selected Publications

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