Coronavirus (COVID-19) Information and Resources

Information on the impact of coronavirus (COVID-19) on patient care and School/University operations. Plus, resources for the Penn Dental Medicine community and alumni.

Ongoing Research Projects

Ongoing Projects

Current Projects

The ARMOR Trial: Commensal Oral Microbiota as a Trigger of Oral Mucositis Severity
Principal Investigator(s): Patricia Corby, DDS, MS and Alexander Lin, MD
Study Status: Currently enrolling

The ARMOR Trial is a randomized, controlled trial of a targeted oral care intervention in patients undergoing radiation or chemoradiation for head and neck cancer. The purpose of the study is to test whether this oral care procedure will delay the onset and reduce the severity, duration, and pain of oral mucositis, a debilitating side effect of radiation therapy. Eligible participants will be asked to attend one visit prior to beginning radiation therapy, weekly visits during radiation therapy, and one visit 3 months after completion of radiation therapy. In total, participants will attend approximately 11 visits over the course of approximately 5.5 months.

You may be eligible to participate if you are aged 18 years or older, are scheduled to undergo radiation or chemoradiation for head and neck cancer, have at least 6 natural teeth, and do not require antibiotic pre-medication prior to dental treatment.

If you are interested in learning more, please contact the study team at (917) 586-9089, PDM-ARMORTrial@dental.upenn.edu.

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